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Human adaptation rates and YEC - 6/25/2008 7:35:38 PM
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essentialsaltes
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Although the e-word gets quite a few people here upset, most everyone seems to find a certain amount of random shuffling, mutation, adaptation and descent acceptable, at least as long as the micro doesn't get too macro. It's kind of old news, but a recent Scientific American article (only a preview available for free, I'm afraid) goes over the most recent research into tracing the human lineage through objective genetic markers shared among different ethnic groups. These changes fall into a cladogram with Africa at its root and Polynesia and the New World at the most distant twigs. This genetic evidence falls in line with our understanding from archaeological and anthropological evidence that humans originated in Africa and reached the New World and the Pacific Islands most recently. From empirical knowledge of rates of genetic change, scientists can make estimates of the timeline for humanity's spread over the earth. This system places an approximate date of 10,000 years ago for the introduction of mankind into the New World, which accords reasonably well with the standard date of 13000 years ago for Clovis sites. The earliest migrations have genetically estimated dates of about 60,000 years ago. So, if you accept that 1) microevolution can occur 2) 'relatedness' can be traced through genetics by comparing how much microevolution 'separates' two gene pools 3) Current experiments have determined an approximate rate of genetic change Then the combination of these leads to a conclusion that requires tens of thousands of years of human adaptation, contradicting a YE position. This line of evidence does not require any naughty macroevolution: our African ancestors were fully human. This only relies on microevolution and empirical data.
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"My object in all arguments is not to make any preconceived opinion of mine seem right, but merely to discover and establish the truth, whatever the truth may be." -- HP Lovecraft, letter to Robert E. Howard 7/27-28/34
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RE: Human adaptation rates and YEC - 6/25/2008 9:58:18 PM
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Aristocrat
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quote:
ORIGINAL: essentialsaltes This line of evidence does not require any naughty macroevolution: our African ancestors were fully human. This only relies on microevolution and empirical data. So does that mean that the Garden of Eden was in Africa?
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I find it odd that ID proponents call evolution materialistic and then take the materialistic approach to finding the ID or Creator.
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RE: Human adaptation rates and YEC - 6/26/2008 1:12:49 PM
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EStan
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quote:
So does that mean that the Garden of Eden was in Africa? I think one could assume so. We know that, historically, Old Testament events from Abraham forward took place in northern Africa.
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Eternal Father, grant that through the tears of repentance I may see more clearly the brightness and glories of the saving cross.
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RE: Human adaptation rates and YEC - 6/26/2008 1:26:46 PM
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DanJames
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quote:
ORIGINAL: EStan quote:
So does that mean that the Garden of Eden was in Africa? I think one could assume so. We know that, historically, Old Testament events from Abraham forward took place in northern Africa. No, the Garden of Eden does not exist any longer. It's buried along with everything else that existed at the time.
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RE: Human adaptation rates and YEC - 6/26/2008 1:34:36 PM
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DanJames
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quote:
ORIGINAL: essentialsaltes So, if you accept that 1) microevolution can occur 2) 'relatedness' can be traced through genetics by comparing how much microevolution 'separates' two gene pools 3) Current experiments have determined an approximate rate of genetic change Then the combination of these leads to a conclusion that requires tens of thousands of years of human adaptation, contradicting a YE position. This line of evidence does not require any naughty macroevolution: our African ancestors were fully human. This only relies on microevolution and empirical data. "Relatedness" can certainly be traced through genetics. I personally don't think that we can take current mutation rates, however well known, and extrapolate that to mean that we know all mutation rates throughout all space and time. We don't know what the rates of mutations have always been. I can look at a genome of a Tomato plant and compare it to a genome of a Potato plant and say, "Hey these two are pretty related". But that doesn't tell me how long ago they branched off. Heck, it doesn't even tell me that they ever branched off! It just shows me that the two have very similar genomes. It tells me that they have very similar biological functions, some of which have been crippled through mutations. I just don't think that we can make a very accurate clock, no matter how accurately we can calculate current mutation rates. We just don't know what our ancestors' genome had to put up with at the time.
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RE: Human adaptation rates and YEC - 6/26/2008 2:07:45 PM
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GroupW
Posts: 2911
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From: Up in the hills of Colorado (very BIG hills...)
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quote:
ORIGINAL: essentialsaltes Although the e-word gets quite a few people here upset, most everyone seems to find a certain amount of random shuffling, mutation, adaptation and descent acceptable, at least as long as the micro doesn't get too macro. It's kind of old news, but a recent Scientific American article (only a preview available for free, I'm afraid) goes over the most recent research into tracing the human lineage through objective genetic markers shared among different ethnic groups. These changes fall into a cladogram with Africa at its root and Polynesia and the New World at the most distant twigs. This genetic evidence falls in line with our understanding from archaeological and anthropological evidence that humans originated in Africa and reached the New World and the Pacific Islands most recently. From empirical knowledge of rates of genetic change, scientists can make estimates of the timeline for humanity's spread over the earth. This system places an approximate date of 10,000 years ago for the introduction of mankind into the New World, which accords reasonably well with the standard date of 13000 years ago for Clovis sites. The earliest migrations have genetically estimated dates of about 60,000 years ago. So, if you accept that 1) microevolution can occur 2) 'relatedness' can be traced through genetics by comparing how much microevolution 'separates' two gene pools 3) Current experiments have determined an approximate rate of genetic change Then the combination of these leads to a conclusion that requires tens of thousands of years of human adaptation, contradicting a YE position. This line of evidence does not require any naughty macroevolution: our African ancestors were fully human. This only relies on microevolution and empirical data. You're not referring to "The Seven Daughters of Eve" by any chance, are you? (Enjoyed that book immensely)
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RE: Human adaptation rates and YEC - 6/26/2008 2:23:37 PM
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essentialsaltes
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quote:
ORIGINAL: DanJames quote:
ORIGINAL: essentialsaltes So, if you accept that 1) microevolution can occur 2) 'relatedness' can be traced through genetics by comparing how much microevolution 'separates' two gene pools 3) Current experiments have determined an approximate rate of genetic change Then the combination of these leads to a conclusion that requires tens of thousands of years of human adaptation, contradicting a YE position. This line of evidence does not require any naughty macroevolution: our African ancestors were fully human. This only relies on microevolution and empirical data. "Relatedness" can certainly be traced through genetics. I personally don't think that we can take current mutation rates, however well known, and extrapolate that to mean that we know all mutation rates throughout all space and time. We don't know what the rates of mutations have always been. I can look at a genome of a Tomato plant and compare it to a genome of a Potato plant and say, "Hey these two are pretty related". But that doesn't tell me how long ago they branched off. Heck, it doesn't even tell me that they ever branched off! It just shows me that the two have very similar genomes. It tells me that they have very similar biological functions, some of which have been crippled through mutations. I just don't think that we can make a very accurate clock, no matter how accurately we can calculate current mutation rates. We just don't know what our ancestors' genome had to put up with at the time. I think I understand your position. You accept 1 & 2, but not the dating method provided by 3. (well, you quibble about #2 -- whether genetic similarity can show relatedness, but in the case of humans for this thread, I don't think you're suggesting we're not all related.) But it seems that your objection to 3 is mainly that you have already adopted a YE position that requires a 'faster clock'. You say that "We just don't know what our ancestors' genome had to put up with at the time," but we have no reason (as far as I know) to believe that anything was significantly different. Sure, we can't *know* whether our cellular machinery just 'decided' to make a lot more errors than usual a few thousand years ago, and there are all sorts of other extraneous possibilities that we could never know about. But these objections have no basis in evidence; they are just objections based on unobserved possibilities. Going this route is to say that, because we can't know everything, we can never know anything. The fact that these molecular clocks give ages in the same range as archeological and radiocarbon evidence adds strength to their joint conclusion. Separate lines of evidence produce the same age. This consistency helps to justify the scientific extrapolation. As always, this is not proof; but this is the best scientific explanation.
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"My object in all arguments is not to make any preconceived opinion of mine seem right, but merely to discover and establish the truth, whatever the truth may be." -- HP Lovecraft, letter to Robert E. Howard 7/27-28/34
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RE: Human adaptation rates and YEC - 6/26/2008 2:26:28 PM
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essentialsaltes
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Joined: 10/14/2007
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quote:
ORIGINAL: GroupW You're not referring to "The Seven Daughters of Eve" by any chance, are you? (Enjoyed that book immensely) Not specifically. I haven't read it. But (judging from a quick scan of a review) I think the non-fictional part of Seven Daughters covers similar ground to what I'm talking about.
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"My object in all arguments is not to make any preconceived opinion of mine seem right, but merely to discover and establish the truth, whatever the truth may be." -- HP Lovecraft, letter to Robert E. Howard 7/27-28/34
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RE: Human adaptation rates and YEC - 6/26/2008 2:29:45 PM
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GroupW
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From: Up in the hills of Colorado (very BIG hills...)
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quote:
ORIGINAL: essentialsaltes quote:
ORIGINAL: GroupW You're not referring to "The Seven Daughters of Eve" by any chance, are you? (Enjoyed that book immensely) Not specifically. I haven't read it. But (judging from a quick scan of a review) I think the non-fictional part of Seven Daughters covers similar ground to what I'm talking about. The book would be better if he'd left off the fictional stories at the end. Seemed to detract from his basic intent. I quit reading it once the facts were done.
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RE: Human adaptation rates and YEC - 6/26/2008 8:01:10 PM
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essentialsaltes
Posts: 1083
Joined: 10/14/2007
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Curiously enough, Smithsonian magazine has a similar article this month. You can read it all online.
_____________________________
"My object in all arguments is not to make any preconceived opinion of mine seem right, but merely to discover and establish the truth, whatever the truth may be." -- HP Lovecraft, letter to Robert E. Howard 7/27-28/34
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RE: Human adaptation rates and YEC - 6/27/2008 10:48:14 AM
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Method
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Joined: 9/19/2007
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quote:
ORIGINAL: DanJames I personally don't think that we can take current mutation rates, however well known, and extrapolate that to mean that we know all mutation rates throughout all space and time. We don't know what the rates of mutations have always been. But we can make predictions about what we should see if mutations rates were the same then as they are now. The fossil evidence indicates that the human and chimp lineages split about 5-7 million years ago. Therefore, we can produce two independent data sets: the mutation rate needed to produce the divergence seen in pseudogenes (which change through genetic drift and are therefore good markers for mutation rates) and the observed mutation rate. If these two data sets match then this is strong evidence that the human mutation rate has been the same for the last 5-7 million years. Guess what? This study has been done. quote:
Hum Mutat. 2003 Jan;21(1):12-27. Direct estimates of human per nucleotide mutation rates at 20 loci causing Mendelian diseases. Kondrashov AS. National Center for Biotechnology Information, NIH, Bethesda, Maryland 20892, USA. Kondrashov@ncbi.nlm.nih.gov I estimate per nucleotide rates of spontaneous mutations of different kinds in humans directly from the data on per locus mutation rates and on sequences of de novo nonsense nucleotide substitutions, deletions, insertions, and complex events at eight loci causing autosomal dominant diseases and 12 loci causing X-linked diseases. The results are in good agreement with indirect estimates, obtained by comparison of orthologous human and chimpanzee pseudogenes. The average direct estimate of the combined rate of all mutations is 1.8x10(-8) per nucleotide per generation, and the coefficient of variation of this rate across the 20 loci is 0.53. Single nucleotide substitutions are approximately 25 times more common than all other mutations, deletions are approximately three times more common than insertions, complex mutations are very rare, and CpG context increases substitution rates by an order of magnitude. There is only a moderate tendency for loci with high per locus mutation rates to also have higher per nucleotide substitution rates, and per nucleotide rates of deletions and insertions are statistically independent on the per locus mutation rate. Rates of different kinds of mutations are strongly correlated across loci. Mutational hot spots with per nucleotide rates above 5x10(-7) make only a minor contribution to human mutation. In the next decade, direct measurements will produce a rather precise, quantitative description of human spontaneous mutation at the DNA level. Published 2002 Wiley-Liss, Inc. PMID: 12497628 [PubMed - indexed for MEDLINE] Therefore, the assumption that mutation rates were close to modern values is a solid and well tested assumption. quote:
I just don't think that we can make a very accurate clock, no matter how accurately we can calculate current mutation rates. We just don't know what our ancestors' genome had to put up with at the time. But we do know what type of mutation rates are necessary to produce the divergence we do see.
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